During preformulation studies of pharmaceutical dosage forms, physical characterization and analysis techniques are\r\nvery useful to detect physical or chemical incompatibilities between the drug and excipients of interest that might interfere with\r\nefficacy and safety of the final drug product. In this study, an approach to possible physical interaction between olanzapine and\r\nguar gum is presented. For the investigation purpose; molecular level property, particulate level property and thermal methods\r\nof analysis have been assessed. Results of FTIR, XRD, DSC and TG analysis studies indicated that olanzapine had compatibility\r\nwith guar gum.
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